The reactor pressure vessel (RPV) in a light-water reactor (LWR) represents the first line of defense against a release of radiation in case of an accident. Thus, regulations, which govern the operation of commercial nuclear power plants, require conservative margins of fracture toughness, both during normal operation and under accident scenarios. In the unirradiated condition, the RPV has sufficient fracture toughness such that failure is implausible under any postulated condition, including pressurized thermal shock (PTS) in pressurized water reactors (PWR).